menu_book Anatomy • 12 min read

Pre-Zygomatic Space: Anatomy Applied to Endomidface

Dr. Robério Brandão

Dr. Robério Brandão

Creator of Face Moderna®

Updated January 1, 2026

The pre-zygomatic space is one of the pillars of facial rejuvenation surgery. Deep knowledge of its anatomy and how to access it safely is essential to obtain natural and lasting results, especially in the Direct Vision Endomidface technique.

This article will guide you through the complexities of the pre-zygomatic space, exploring its importance in the Modern Face philosophy, and offering practical information for surgeons seeking to improve their skills in Endomidface.

What Is the Pre-Zygomatic Space?

The pre-zygomatic space, as the name suggests, is an anatomical region located anterior to the zygomatic bone, one of the main components of the facial bone structure. This space is part of the midface and plays a crucial role in the contour and projection of the malar region, commonly known as the cheekbone.

Anatomical Delimitations

To fully understand the pre-zygomatic space, it is essential to know its boundaries:

  • Anteriorly: Skin and subcutaneous tissue
  • Posteriorly: Periosteum of the zygomatic bone
  • Superiorly: Orbicularis oculi muscle
  • Inferiorly: Zygomaticus major and minor muscles

It is important to note that within the pre-zygomatic space, we also find fat compartments that contribute to facial volume and shape.

The Importance of the Pre-Zygomatic Space in Endomidface

In the context of Endomidface, the pre-zygomatic space becomes a central point for obtaining effective and natural results. The surgical technique aims to access and manipulate this space to reposition facial tissues, restoring lost volume and improving facial contour.

As Dr. Robério Brandão, creator of the Modern Face philosophy, explains:

“The pre-zygomatic space is the key to effective facial rejuvenation. By accessing and manipulating it correctly, we can restore lost volume and improve facial contour naturally and permanently.”

The Relationship with Retaining Ligaments

The pre-zygomatic space is closely related to the facial retaining ligaments, fibrous structures that connect the skin to deeper tissues. The main retaining ligaments in the midface region include:

  • Zygomatic ligament: Strong ligament extending from the zygomatic bone to the skin, influencing malar projection.
  • Orbito-malar ligament: Located in the lower orbital region, contributes to lower eyelid support and nasojugal groove definition.

During Endomidface, the surgeon must carefully navigate around these ligaments, partially releasing them to allow tissue mobilization, but preserving their integrity to ensure adequate support and avoid artificial results.

Accessing the Pre-Zygomatic Space in Direct Vision Endomidface

Direct Vision Endomidface offers a minimally invasive approach to accessing the pre-zygomatic space. The technique uses a discreet incision in the temporal region, allowing the surgeon to work in a deep plane with precision and safety.

Step-by-Step Access

  1. Temporal Incision: Made in the temporal region within the hairline to ensure the scar is practically invisible.
  2. Sub-SMAS Dissection: The surgeon uses delicate instruments to dissect tissues in the sub-SMAS (Superficial Musculoaponeurotic System) plane, a fibromuscular layer surrounding facial muscles.
  3. Identification of Zygomatic Arch: The zygomatic arch serves as an important anatomical guide to orient dissection toward the pre-zygomatic space.
  4. Ligament Release: Zygomatic and orbito-malar ligaments are carefully released to allow tissue mobilization.
  5. Repositioning and Fixation: Midface tissues are repositioned and fixed in a higher position, restoring facial volume and contour.

Endomidface and the “Biological Superglue” of Biostimulators

One of the great advantages of Endomidface is the ability to deal with fibrosis caused by biostimulators, such as Sculptra and Radiesse. These products can create a dense fibrous tissue layer in the SMAS, making dissection difficult and increasing the risk of nerve injuries.

Dr. Robério Brandão’s approach minimizes this risk by accessing the pre-zygomatic space through a different path.

As he explains:

“Most patients who come to us today have already undergone some type of injectable aesthetic procedure. Endomidface allows us to bypass the fibrosis area and work in a safer plane, minimizing complication risk.”

Safe Navigation in the Pre-Zygomatic Space: Essential Tips

Manipulating the pre-zygomatic space requires deep knowledge of facial anatomy and refined surgical technique. Here are some essential tips to ensure procedure safety and success:

  1. Keep Dissection in Correct Plane: The sub-SMAS plane is fundamental to avoid damage to nerves and blood vessels. The tactile sensation of “separating pages of a wet book” is an important indicator that you are in the correct plane.
  2. Avoid Deepening Too Much: Deepening dissection can put the facial nerve and other important structures at risk. Stay attentive to anatomical landmarks and use delicate instruments to avoid injuries.
  3. Respect Retaining Ligaments: Excessive release of ligaments can lead to artificial results and support loss. Release ligaments moderately, only enough to allow tissue mobilization.
  4. Be Careful with Zygomatico-Facial Vein: This vein crosses the pre-zygomatic space and can easily be injured during dissection. Cauterize it carefully to avoid bleeding.
  5. Consider Fat Grafting: In some cases, fat grafting can be used to add volume and improve facial contour. Inject fat carefully to avoid irregularities or asymmetries.

Master Tactile Anatomy

Dr. Robério Brandão emphasizes the importance of tactile anatomy for safe and effective navigation in the pre-zygomatic space. Developing the ability to “feel” anatomical structures with surgical instruments allows the surgeon to work with greater precision and minimize injury risk.


Relevant Anatomy for This Procedure

Anatomical knowledge is fundamental to understand how results are achieved safely and effectively.

Key Structures

The face is composed of layers that must be understood together:

  • Skin: most superficial layer, reflecting aging through wrinkles and laxity
  • Subcutaneous tissue: contains fat that redistributes with age
  • SMAS (Superficial Musculoaponeurotic System): fundamental layer connecting muscles to skin
  • Facial muscles: responsible for expression and dynamic support
  • Retaining ligaments: anchor skin to facial skeleton
  • Facial nerves: control movement and sensitivity

Surgical Planes

In Modern Face philosophy, we work in specific planes:

  • Superficial plane: above SMAS, used in less invasive procedures
  • Deep plane (sub-SMAS): below SMAS, allows more lasting results
  • Subcutaneous plane: used for fat grafting and fat treatment

Why This Matters

Understanding anatomy explains:

  • Why certain procedures last longer than others
  • How natural results are achieved
  • Why surgeon experience is crucial
  • How complications can be avoided

“Respect for anatomy is what separates a natural result from an artificial one. In Modern Face, each structure has its role and must be preserved or repositioned with precision.” — Dr. Robério Brandão

Results and Statistics

Objective data helps establish realistic expectations about the procedure.

Result Durability

Longevity of results depends on multiple factors:

FactorImpact on Durability
Technique usedHigh — deep plane lasts longer
Skin qualityModerate — firmer skin maintains better
Sun exposureHigh — sun accelerates aging
SmokingHigh — smoking significantly harms
Stable weightModerate — fluctuations affect result
GeneticsModerate — individual predisposition

Modern Face Clinical Series Data

  • More than 1,000 facial surgeries without any irreversible motor nerve injury
  • Average recovery time: 10-14 days
  • Return to work: 7-10 days (average)

What to Expect Realistically

  • Immediate: visible improvement, but with edema
  • 30 days: result developing
  • 90 days: almost definitive result
  • 6 months: final result stabilized

“Numbers are important, but every face is unique. Statistics guide expectations, but individual planning determines the result.” — Dr. Robério Brandão

Conclusion

The pre-zygomatic space is a fundamental component of facial anatomy and plays a crucial role in midface rejuvenation. The Direct Vision Endomidface technique, developed by Dr. Robério Brandão, offers a minimally invasive and safe approach to accessing and manipulating this space, restoring lost volume and improving facial contour.

By mastering pre-zygomatic space anatomy and following safety tips presented in this article, surgeons can improve their skills and offer their patients natural and lasting results.

To deepen your knowledge and master the Direct Vision Endomidface technique, we invite you to check out the Facelift Mastery course, where Dr. Robério Brandão shares his vast experience and offers a complete guide to success in facial rejuvenation surgery.

FAQ (Frequently Asked Questions)

What is the pre-zygomatic space?

It is a key anatomical space in the midface, located anterior to the zygomatic bone and essential in Endomidface.

What is the importance of the pre-zygomatic space in Endomidface?

It allows the repositioning of midface tissues, contributing to facial rejuvenation and improving malar contour.

Which anatomical structures delimit the pre-zygomatic space?

It is delimited by the orbicularis oculi muscle, the zygomaticus major and minor muscles, and the periosteum of the zygomatic bone.

How does Dr. Robério Brandão access the pre-zygomatic space in Endomidface?

Through a temporal portal, following the sub-SMAS plane and contouring the zygomatic arch.

What precautions are necessary when manipulating the pre-zygomatic space?

Keep dissection in the correct plane (sub-SMAS) and avoid deepening to not damage nerve and vascular structures.

What are retaining ligaments and what is their relationship with the pre-zygomatic space?

They are structures that anchor the face to the skeleton. In Endomidface, deep dissection navigates around/under these ligaments to allow tissue mobilization.



⚠️ Disclaimer

This content is educational and represents the author’s technical opinion based on documented clinical experience. Surgical decisions should be individualized.

Author: Dr. Robério Brandão, CRM-CE 8596 Last update: January 2026

Frequently Asked Questions

What is the pre-zygomatic space?

expand_more

It is a key anatomical space in the midface, located anterior to the zygomatic bone and essential in Endomidface.

What is the importance of the pre-zygomatic space in Endomidface?

expand_more

It allows the repositioning of midface tissues, contributing to facial rejuvenation and improving malar contour.

Which anatomical structures delimit the pre-zygomatic space?

expand_more

It is delimited by the orbicularis oculi muscle, the zygomaticus major and minor muscles, and the periosteum of the zygomatic bone.

How does Dr. Robério Brandão access the pre-zygomatic space in Endomidface?

expand_more

Through a temporal portal, following the sub-SMAS plane and contouring the zygomatic arch.

What precautions are necessary when manipulating the pre-zygomatic space?

expand_more

Keep dissection in the correct plane (sub-SMAS) and avoid deepening to not damage nerve and vascular structures.

What are retaining ligaments and what is their relationship with the pre-zygomatic space?

expand_more

They are structures that anchor the face to the skeleton. In Endomidface, deep dissection navigates around/under these ligaments to allow tissue mobilization.

Want to Master These Techniques?

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